Platelet immunology and alloimmunization
نویسنده
چکیده
Platelets express a variety of immunogenic markers on the cell surface. Some of these antigens are shared with other cell types as in the case of HLA antigens, which are shared with virtually all nucleated cells in the body, whereas others are observed to be essentially platelet specific. This chapter reviews the antigens expressed on platelets, the various patterns of alloimmunization to these antigens, and their impact on platelet transfusion responses. Strategies to treat and prevent alloimmunization are summarized.
منابع مشابه
Iranian Turkmen blood donors determining the HPA-1 gene frequency in 1397
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